Clinical Sample Collection

Subcutaneous xenograft efficacy models are popular because these are easy to manage, easy to establish, and are very effective for the treatment of tumor. Most commonly, head and neck cancers are the most prevalent tumor. Despite of the researches and advanced technology, the patients with head and neck tumors have a tough way to go. Despite of many treatments given to the head and neck cancer patients, their chances of survival is comparatively less than other cases. One of the most basic causes for the lack of treatment for the patients with head and neck disease is the lack of reliable animal models of head and neck cancer metastasis. The cancer tissue xenograft and transplantable tumor lines derived from those type of xenograft are very similar to the donor tissues and they have the same genetic and epigenetic characteristics and also same in the case of drugs used on them to some extent. In a research, it is found that patient derived xenograft can be used for the therapy of cancer. Subcutaneous tumor models are very advantageous than other models because of their ease of tumor establishment, reproducibility and measurement. It is always admissible to use than other models.