There are several research academies and laboratories that are performing various tests and studies to cure cancer. Even when the technology combined with medicine has produced miraculous results with other diseases, cancer seems to be unmoved, despite the efforts of several experts. The present patient derived tumor xenograft efficacy models are depending on the cell lines of diseased patients. Even though they are considered to be an ideal choice for conducting basic level research or experiments, they do not give a high efficacy. This has in turn resulted in a slight setback, which means the patient derived tumor xenograft efficacy models are not always effective for clinical research, however they are important to carry on the tests to advanced phases.
In the patient derived xenograft models, a small quantity of tumor is derived from the sufferer and injected into the immune deficient mice. Then the various drugs are tested against the malignances. This way the tests must offer some concrete results, which are otherwise not possible by usage of commercial cells. Moreover, the patient derived tumor xenograft efficacy models are used to screen and select drugs and drug products for other in vivo assessments. Hence, this test is more like a stepping stone to the larger and more practical tests, where the tests will be conducted over live patients.

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